Great perspectives from everyone. I might as well opine on the subject, too.
Internet Explorer was always a pain for me, not that it was difficult, but it often led to frequent computer hassles, frequent family tech support phone calls and ultimately was the perfect gateway to contract Malware and Spyware on computers.
Before Spyware and Malware hit their prime-time, I did respect IE for its ease of use and functionality. However, even today with all the latest patches and updates, IE is still a security risk on people's machines.
I discovered Firefox and have used it since 0.9 (Mid 2004), and haven't switched back. It's speed and reliability -- as well as security -- has made it a top choice for me. Does that mean it's perfect, no, not by a long shot, but it makes Web browsing much better than it was for IE in the peak of Malware. I stick to the browser because it's open-source and leverages the input from thousands of developers world wide, making it nearly the most secure and efficient Web browser today.
Firefox does have it's drawbacks, too. For instance, third-party plugin support (Flash, RealPlayer and Windows Media) are often a challenge for the browser to offer native support for users. However, with each release and numerous addons are made available; the browser is becoming just a little more sweeter to use.
I've used Opera, Avant and other Web browsers; but I find that Firefox balances speed, usability and reliability best in my experience. Perhaps, Internet Explorer 8 will be better, but we have to cross our fingers before we cross that bridge.
~Joe